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SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease.


ABSTRACT: We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR.

SUBMITTER: Perera RAPM 

PROVIDER: S-EPMC7588524 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease.

Perera Ranawaka A P M RAPM   Tso Eugene E   Tsang Owen T Y OTY   Tsang Dominic N C DNC   Fung Kitty K   Leung Yonna W Y YWY   Chin Alex W H AWH   Chu Daniel K W DKW   Cheng Samuel M S SMS   Poon Leo L M LLM   Chuang Vivien W M VWM   Peiris Malik M  

Emerging infectious diseases 20200804 11


We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR. ...[more]

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