GAGA Regulates Border Cell Migration in Drosophila.

ABSTRACT: Collective cell migration is a complex process that happens during normal development of many multicellular organisms, as well as during oncological transformations. In Drosophila oogenesis, a small set of follicle cells originally located at the anterior tip of each egg chamber become motile and migrate as a cluster through nurse cells toward the oocyte. These specialized cells are referred to as border cells (BCs) and provide a simple and convenient model system to study collective cell migration. The process is known to be complexly regulated at different levels and the product of the slow border cells (slbo) gene, the C/EBP transcription factor, is one of the key elements in this process. However, little is known about the regulation of slbo expression. On t

SUBMITTER: Ogienko AA 

PROVIDER: S-EPMC7589894 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature