Intraoral Microbial Metabolism and Association with Host Taste Perception.

ABSTRACT: Metabolomics has been identified as a means of functionally assessing the net biological activity of a particular microbial community. Considering the oral microbiome, such an approach remains largely underused. While the current knowledge of the oral microbiome is constantly expanding, there are several deficits in knowledge particularly relating to their interactions with their host. This work uses nuclear magnetic resonance spectroscopy to investigate metabolic differences between oral microbial metabolism of endogenous (i.e., salivary protein) and exogenous (i.e., dietary carbohydrates) substrates. It also investigated whether microbial generation of different metabolites may be associated with host taste perception. This work found that in the absence of exogenous substrate, oral bact

SUBMITTER: Gardner A 

PROVIDER: S-EPMC7590808 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature