Estimating peak height velocity in individuals: a comparison of statistical methods.

ABSTRACT:

Background

Estimates pertaining to the timing of the adolescent growth spurt (e.g. peak height velocity; PHV), including age at peak height velocity (aPHV), play a critical role in the diagnosis, treatment, and management of skeletal growth and/or developmental disorders. Yet, distinct statistical methodologies often result in large estimate discrepancies.

Aim

The aim of the present study was to assess the advantages and disadvantages of three modelling methodologies for height as well as to determine how estimates derived from these methodologies may differ, particularly those that may be useful in paediatric clinical practice.

Subjects and methods

Height data from 686 individuals of the Fels Longitudinal Study were modelled using 5th order polynomials, natural cubic

SUBMITTER: Boeyer ME 

PROVIDER: S-EPMC7590904 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature