Detection of Ascaris lumbricoides infection by ABA-1 coproantigen ELISA.

ABSTRACT: Intestinal worms, or soil-transmitted helminths (STHs), affect hundreds of millions of people in all tropical and subtropical regions of the world. The most prevalent STH is Ascaris lumbricoides. Through large-scale deworming programs, World Health Organization aims to reduce morbidity, caused by moderate-to-heavy intensity infections, below 2%. In order to monitor these control programs, stool samples are examined microscopically for the presence of worm eggs. This procedure requires well-trained personnel and is known to show variability between different operators interpreting the slides. We have investigated whether ABA-1, one of the excretory-secretory products of A. lumbricoides can be used as a coproantigen marker for infection with this parasite. Polyclonal antibodies were generate

SUBMITTER: Lagatie O 

PROVIDER: S-EPMC7591086 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature