No effect of gestational diabetes or pre-gestational obesity on 6-year offspring left ventricular function-RADIEL study follow-up.

ABSTRACT:

Aims

We aimed to investigate associations between pre-pregnancy obesity, gestational diabetes (GDM), offspring body composition, and left ventricular diastolic and systolic function in early childhood.

Methods

This is an observational study, including 201 mother-child pairs originating from the Finnish Gestational Diabetes Prevention Study (RADIEL; 96 with GDM, 128 with pre-pregnancy obesity) with follow-up from gestation to 6-year postpartum. Follow-up included dyads anthropometrics, body composition, blood pressure, and child left ventricular function with comprehensive echocardiography (conventional and strain imaging).

Results

Offspring left ventricular diastolic and systolic function was not associated with gestational glucose concentrations, GDM, or pregravida o

SUBMITTER: Litwin L 

PROVIDER: S-EPMC7591425 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature