Infant wheezing and prenatal antibiotic exposure and mode of delivery: a prospective birth cohort study.

ABSTRACT: Introduction: Assessments on whether prenatal antibiotic exposure and mode of delivery increase the risk of wheezing in infants and toddlers are inconsistent. Our goal is to evaluate the association between prenatal antibiotic use and Cesarean section with three subtypes of wheezing in infancy.Methods: An ongoing prospective three generations cohort study provides data on prenatal antibiotic use and mode of delivery. Respective questionnaire data was used to distinguish three subtypes of wheezing: any wheezing, infectious wheezing, and noninfectious wheezing. Repeated measurements of wheezing at 3, 6, and 12 months were analyzed using generalized estimation equations. Latent transition analysis assessed patterns of infant wheezing development in the first year of life.Resu

SUBMITTER: Higgins D 

PROVIDER: S-EPMC7592169 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature