Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction.

ABSTRACT: Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiology of HFpEF and is an important contributor to exercise intolerance in HFpEF patients. The effects of exercise training on left ventricular diastolic function in HFpEF patients have been examined in several randomised clinical trials. Meta-analysis of the trials indicates that exercise training can provide clinically relevant improvements in exercise capacity without significant change in left ventricular structure or function in HFpEF patients. Further studies are necessary to elucidate the exa

SUBMITTER: Fukuta H 

PROVIDER: S-EPMC7592458 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature