Exploring Bacterial Microcompartments in the Acetogenic Bacterium Acetobacterium woodii.

ABSTRACT: The strictly anaerobic acetogenic bacterium Acetobacterium woodii is metabolically diverse and grows on variety of substrates which includes H₂ + CO₂, sugars, alcohols and diols. It is unique in producing bacterial microcompartments (BMC) during growth on different substrates such as 1,2-propanediol, 2,3-butanediol, ethanol or fructose. In this study, we analyzed the genetic organization and expression of the BMC genes within the A. woodii genome, the previously described 18 gene pdu cluster as well as four other cluster potentially encoding one or two shell proteins. Expression analysis of respective gene clusters revealed that the pdu gene cluster is highly expressed during growth on 1,2-PD, 2,3-BD, ethanol and ethylene glycol. The promot

SUBMITTER: Chowdhury NP 

PROVIDER: S-EPMC7593272 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature