Neuromodulation Techniques in Phantom Limb Pain: A Systematic Review and Meta-analysis.

ABSTRACT:

Objective

To evaluate the effects of neuromodulation techniques in adults with phantom limb pain (PLP).

Methods

A systematic search was performed, comprising randomized controlled trials (RCTs) and quasi-experimental (QE) studies that were published from database inception to February 2019 and that measured the effects of neuromodulation in adults with PLP. Hedge's g effect size (ES) and 95% confidence intervals were calculated, and random-effects meta-analyses were performed.

Results

Fourteen studies (nine RCTs and five QE noncontrolled studies) were included. The meta-analysis of RCTs showed significant effects for i) excitatory primary motor cortex (M1) stimulation in reducing pain after stimulation (ES = -1.36, 95% confidence interval [CI] = -2.26 to -0.45); ii) a

SUBMITTER: Pacheco-Barrios K 

PROVIDER: S-EPMC7593798 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature