Human Amniotic Epithelial Stem Cells: A Promising Seed Cell for Clinical Applications.

ABSTRACT: Perinatal stem cells have been regarded as an attractive and available cell source for medical research and clinical trials in recent years. Multiple stem cell types have been identified in the human placenta. Recent advances in knowledge on placental stem cells have revealed that human amniotic epithelial stem cells (hAESCs) have obvious advantages and can be used as a novel potential cell source for cellular therapy and clinical application. hAESCs are known to possess stem-cell-like plasticity, immune-privilege, and paracrine properties. In addition, non-tumorigenicity and a lack of ethical concerns are two major advantages compared with embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). All of the characteristics mentioned above and other additional advantages, inc

SUBMITTER: Qiu C 

PROVIDER: S-EPMC7594030 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature