Antiangiogenic Activity of Flavonoids: A Systematic Review and Meta-Analysis.

ABSTRACT: Abstract: An imbalance of angiogenesis contributes to many pathologies such as cancer, arthritis and retinopathy, hence molecules that can modulate angiogenesis are of considerable therapeutic importance. Despite many reports on the promising antiangiogenic properties of naturally occurring flavonoids, no flavonoids have progressed to the clinic for this application. This systematic review and meta-analysis therefore evaluates the antiangiogenic activities of a wide range of flavonoids and is presented in two sections. The first part of the study (Systematic overview) included 402 articles identified by searching articles published before May 2020 using ScienceDirect, PubMed and Web of Science databases. From this initial search, different classes of flavonoids with antiangiogenic activiti

SUBMITTER: Khater M 

PROVIDER: S-EPMC7594036 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature