Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis.

ABSTRACT: This study is a bioinformatics assay on the microbial genome of Bacteroides thetaiotaomicron. The study focuses on the problem of quorum sensing as a result of adverse factors such as chemotherapy and antibiotic therapy. In patients with severe intestinal diseases, two strains of microorganisms were identified that were distinguished as new. Strains were investigated by conducting genome sequencing. The current concepts concerned with the quorum sensing system regulation by stationary-phase sigma factor and their coregulation of target genes in B. thetaiotaomicron were considered. The study suggested using bioinformatics data for the diagnosis of gastrointestinal disorders. In the course of the study, 402 genes having a greater than twofold change were identified with the 95%

SUBMITTER: Wu ZC 

PROVIDER: S-EPMC7594123 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature