Cell Enriched Autologous Fat Grafts to Follicular Niche Improves Hair Regrowth in Early Androgenetic Alopecia.

ABSTRACT:

Background

Adipose and adipose derived regenerative cells (ADRCs) play an increasing role in androgenetic alopecia.

Objectives

The authors sought to evaluate the safety and feasibility of fat grafts enriched with ADRCs in early androgenetic alopecia.

Methods

Seventy-one patients were treated: 16 with Puregraft fat and 1.0 × 106 ADRCs/cm2 scalp; 22 with Puregraft fat and 0.5 × 106 ADRCs/cm2 scalp, 24 with Puregraft fat alone, and 9 with saline control. Treatments were delivered into the skin and subcutaneous layer of the scalp. A total of 40 cm2 of scalp was treated and macrophotography and global photography were obtained at baseline and at 6, 24, and 52 weeks.

Results

A total of 71 patients tolerated the procedures well. No unanticipated associated adverse eve

SUBMITTER: Kuka G 

PROVIDER: S-EPMC7594181 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature