Local use of dexamethasone in the treatment of ocular myasthenia gravis.

ABSTRACT:

Background

At present, patients with ocular myasthenia gravis (OMG) are typically treated with systemic drugs. We investigated the use of dexamethasone injected in the peribulbar region or extraocular muscle to treat patients with OMG.

Methods

Patients with OMG were given dexamethasone via peribulbar injection or direct injection into the main paralyzed extraocular muscles, once a week, for 4-6 weeks. The severity of diplopia, blepharoptosis, eye position, and eye movement were evaluated before and after treatment. The duration of follow-up time was ≥6 months.

Results

Among the 14 patients with OMG who received this treatment, mean age was 38.7 ± 29.7 years. After treatment, symptoms were relieved in 12 patients (85.7%), 1 patient (7.1%) had partial response to treatm

SUBMITTER: Shi M 

PROVIDER: S-EPMC7594471 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature