Utility of Air Bladder-Derived Nanostructured ECM for Tissue Regeneration.

ABSTRACT: Exploration for ideal bone regeneration materials still remains a hot research topic due to the unmet clinical challenge of large bone defect healing. Bone grafting materials have gradually evolved from single component to multiple-component composite, but their functions during bone healing still only regulate one or two biological processes. Therefore, there is an urgent need to develop novel materials with more complex composition, which convey multiple biological functions during bone regeneration. Here, we report an naturally nanostructured ECM based composite scaffold derived from fish air bladder and combined with dicalcium phosphate (DCP) microparticles to form a new type of bone grafting material. The DCP/acellular tissue matrix (DCP/ATM) scaffold demonstrated porous structure wit

SUBMITTER: Wang J 

PROVIDER: S-EPMC7594528 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature