Subclinical macro and microvascular disease is differently associated with depressive symptoms in men and women: Findings from the SABRE population-based study.

ABSTRACT:

Background and aims

Mechanisms underlying the association between cardiovascular disease (CVD) and depression are unknown, and sex differences understudied. We investigated associations between a comprehensive set of measures of macro and microvascular disease and depressive symptoms in older men and women.

Methods

We performed cross-sectional analyses of the SABRE (Southall And Brent REvisited) population-based study. Participants (1396) attended clinic between 2008 and 2011 for assessment of subclinical macrovascular (carotid ultrasound, echocardiography, cerebral magnetic resonance imaging) and microvascular (retinopathy, nephropathy) disease, and depression.

Results

Mean age of 1396 participants was 69.5 years, and 76.2% were male. The median (interquartile range)

SUBMITTER: Wang J 

PROVIDER: S-EPMC7594642 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature