Single-scale time-dependent window-sizes in sliding-window dynamic functional connectivity analysis: A validation study.

ABSTRACT: During the past ten years, dynamic functional connectivity (FC) has been extensively studied using the sliding-window method. A fixed window-size is usually selected heuristically, since no consensus exists yet on choice of the optimal window-size. Furthermore, without a known ground-truth, the validity of the computed dynamic FC remains unclear and questionable. In this study, we computed single-scale time-dependent (SSTD) window-sizes for the sliding-window method. SSTD window-sizes were based on the frequency content at every time point of a time series and were computed without any prior information. Therefore, they were time-dependent and data-driven. Using simulated sinusoidal time series with frequency shifts, we demonstrated that SSTD window-sizes captured the time-dependent period

SUBMITTER: Zhuang X 

PROVIDER: S-EPMC7594665 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature