Per- and polyfluoroalkyl substances in drinking water and birthweight in the US: A county-level study.

ABSTRACT:

Background

Per- and polyfluoroalkyl substances (PFAS) are ubiquitous in the serum of the general US population, and were detected in public water systems serving approximately 16.5 million US residents during 2013-2015. Low birthweight was associated with PFAS exposures in previous studies.

Methods

Birthweights for singleton births during 2013-2015 were obtained from CDC WONDER, multiply stratified by county, maternal age, race, education, smoking status, and parity. PFAS water concentrations were obtained from EPA UCMR3 database and aggregated by county. Multiple regression weighted by inverse variance was used to produce effect estimates equivalent to those that would be obtained from individual-level data on birthweight and confounders.

Results

Adjusting for strati

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC7595209 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature