Ferritin in the coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.

ABSTRACT:

Objective

The coronavirus disease 2019 (COVID-19) has rapidly developed into a pandemic. Increased levels of ferritin due to cytokine storm and secondary hemophagocytic lymphohistiocytosis were found in severe COVID-19 patients. Therefore, the aim of this study was to determine the role of ferritin in COVID-19.

Methods

Studies investigating ferritin in COVID-19 were collected from PubMed, EMBASE, CNKI, SinoMed, and WANFANG. A meta-analysis was performed to compare the ferritin level between different patient groups: non-survivors versus survivors; more severe versus less severe; with comorbidity versus without comorbidity; ICU versus non-ICU; with mechanical ventilation versus without mechanical ventilation.

Results

A total of 52 records involving 10 614 COVID-19-conf

SUBMITTER: Cheng L 

PROVIDER: S-EPMC7595919 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature