Regional venous-arterial CO₂ to arterial-venous O₂ content difference ratio in experimental circulatory shock and hypoxia.

ABSTRACT:

Background

Venous-arterial carbon dioxide (CO₂) to arterial-venous oxygen (O₂) content difference ratio (Cv-aCO₂/Ca-vO₂) > 1 is supposed to be both sensitive and specific for anaerobic metabolism. What regional hemodynamic and metabolic parameters determine the ratio has not been clarified.

Objectives

To address determinants of systemic and renal, spleen, gut and liver Cv-aCO₂/Ca-vO₂.

Methods

Post hoc analysis of original data from published experimental studies aimed to address effects of different fluid resuscitation strategies on oxygen transport, lactate metabolism and organ dysfunction in fecal peritonitis and endotoxin infusion, and from animals in cardiac tamponade or hypoxic hypoxia. Systemic an

SUBMITTER: Correa TD 

PROVIDER: S-EPMC7596113 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature