Genomic Diversification, Structural Plasticity, and Hybridization in Leishmania (Viannia) braziliensis.

ABSTRACT: Leishmania (Viannia) braziliensis is an important Leishmania species circulating in several Central and South American countries. Among Leishmania species circulating in Brazil, Argentina and Colombia, L. braziliensis has the highest genomic variability. However, genomic variability at the whole genome level has been only studied in Brazilian and Peruvian isolates; to date, no Colombian isolates have been studied. Considering that in Colombia, L. braziliensis is a species with great clinical and therapeutic relevance, as well as the role of genetic variability in the epidemiology of leishmaniasis, we analyzed and evaluated intraspecific genomic variability of L. braziliensis from Colombian and Bolivian isolates and compared them with Brazilian isol

SUBMITTER: Patino LH 

PROVIDER: S-EPMC7596589 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature