Transcriptomic and functional analyses reveal an antiviral role of autophagy during pepper mild mottle virus infection.

ABSTRACT:

Background

Pepper mild mottle virus (PMMoV) is a member in the genus Tobamovirus and infects mainly solanaceous plants. However, the mechanism of virus-host interactions remains unclear. To explore the responses of pepper plants to PMMoV infection, we analyzed the transcriptomic changes in pepper plants after PMMoV infection using a high-throughput RNA sequencing approach and explored the roles of host autophagy in regulating PMMoV infection.

Results

A total of 197 differentially expressed genes (DEGs) were obtained after PMMoV infection, including 172 significantly up-regulated genes and 25 down-regulated genes. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that most up-regulated DEGs were involved in plant abiotic and b

SUBMITTER: Jiao Y 

PROVIDER: S-EPMC7596970 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature