ICREATE: imaging features of primary and metastatic alveolar soft part sarcoma from the EORTC CREATE study.

ABSTRACT:

Background

Alveolar Soft Part Sarcoma (ASPS) is a rare, slow-growing, but highly vascular soft tissue sarcoma, characterised by a high rate of metastases at presentation. Although imaging features of the primary are well described, less detail is available on the imaging pattern of metastatic ASPS. The EORTC 90101 (CREATE) study assessed the efficacy of Crizotinib in patients with metastatic ASPS and presents a unique opportunity to describe the imaging phenotype of primary and metastatic ASPS, based on prospectively collected imaging.

Methods

A retrospective review of the staging CT scans of 32 patients with ASPS from the CREATE study was undertaken and the imaging features of primary and metastatic disease were assessed.

Results

Imaging of the primary tumour was ava

SUBMITTER: Mcaddy NC 

PROVIDER: S-EPMC7597361 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature