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Prevalence of avian-origin mcr-1-positive Escherichia coli with a potential risk to humans in Tai'an, China.


ABSTRACT: Multidrug-resistant (MDR) Escherichia coli are responsible for difficult-to-treat infections. We sought to determine the prevalence and characteristics of MDR E. coli strains isolated from poultry and clinical patients in the same geographical region. Eighty-seven E. coli strains were isolated from poultry with perihepatitis lesions at different slaughterhouses, and 356 nonrepetitive E. coli strains were isolated from clinical patients. All samples were continuously collected from October to December 2017 in Tai'an, China. The presence of the mcr-1 gene in the strains was assessed by PCR. The genetic relationships of the polymyxin (POL)-resistant E. coli strains were analyzed by pulsed-field gel electrophoresis and multilocus sequence typing. The results indicate that the POL resistance ra

SUBMITTER: Li X 

PROVIDER: S-EPMC7598320 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature