Gut microbiota ecology: Biodiversity estimated from hybrid neutral-niche model increases with health status and aging.

ABSTRACT: In this work we propose an index to estimate the gut microbiota biodiversity using a modeling approach with the aim of describing its relationship with health and aging. The gut microbiota, a complex ecosystem that links nutrition and metabolism, has a pervasive effect on all body organs and systems, undergoes profound changes with age and life-style, and substantially contributes to the pathogenesis of age-related diseases. For these reasons, the gut microbiota is a suitable candidate for assessing and quantifying healthy aging, i.e. the capability of individuals to reach an advanced age, avoiding or postponing major age-related diseases. The importance of the gut microbiota in health and aging has been proven to be related not only to its taxonomic composition, but also to its ecological

SUBMITTER: Sala C 

PROVIDER: S-EPMC7599046 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature