Zika Virus and Arthritis/Arthralgia: A Systematic Review and Meta-Analysis.

ABSTRACT: Dengue, chikungunya and Zika viruses share similar disease features, rendering them difficult to distinguish clinically. Incapacitating arthralgia/arthritis is a specific manifestation associated with chikungunya virus infection. However, the profile of arthralgia/arthritis in Zika virus (ZIKV) cases has not been well characterized. Articles were extracted from PubMed and Scopus databases reporting original data from patients with arthralgia/arthritis, according to the Cochrane Collaboration. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 137 articles reporting ZIKV-associated joint symptoms were reviewed. Arthralgia was more frequently reported (n = 124 from case studies, n = 1779 from population-based studies) than arthritis (n = 7 and n = 121, r

SUBMITTER: Wimalasiri-Yapa BMCR 

PROVIDER: S-EPMC7599580 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature