Impact of Yeast-Derived β-Glucans on the Porcine Gut Microbiota and Immune System in Early Life.

ABSTRACT: Piglets are susceptible to infections in early life and around weaning due to rapid environmental and dietary changes. A compelling target to improve pig health in early life is diet, as it constitutes a pivotal determinant of gut microbial colonization and maturation of the host's immune system. In the present study, we investigated how supplementation of yeast-derived β-glucans affects the gut microbiota and immune function pre- and post-weaning, and how these complex systems develop over time. From day two after birth until two weeks after weaning, piglets received yeast-derived β-glucans or a control treatment orally and were subsequently vaccinated against Salmonella Typhimurium. Faeces, digesta, blood, and tissue samples were collected to study gut microbiota composition and immune f

SUBMITTER: de Vries H 

PROVIDER: S-EPMC7601942 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature