The Core and Distinction of the Gut Microbiota in Chinese Populations across Geography and Ethnicity.

ABSTRACT: The diversity of the human gut microbiota constitutes a fundamental health indicator of different populations. The relative importance of geographical location and ethnicity on the gut microbiota, however, has not been previously addressed. Due to unique ethnic distributions across China, we recruited distinct minority ethnic groups, including Han populations, in each of the seven cities that were explored in this study. We investigated the gut microbiota of 394 healthy subjects (14 groups) from these seven different cities using 16S rRNA sequencing. Our results indicated that both geographical location and ethnicity were major factors. However, geographical location exhibited greater influence than ethnicity on both the composition and diversity of the gut microbiota. In addition, a total

SUBMITTER: Lin D 

PROVIDER: S-EPMC7602275 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature