Newborn Screening Samples for Diabetes Research: An Underused Resource.

ABSTRACT: Inborn errors of metabolism and diabetes share common derangements in analytes of metabolic networks that are tested for in newborn screening, usually performed 48-72 h after birth. There is limited research examining the metabolic imprint of diabetes on newborn screening results. This paper aims to demonstrate the links between diabetes, biochemical genetics and newborn screening in investigating disease pathophysiology in diabetes, provide possible reasons for the lack of research in diabetes in newborn screening and offer recommendations on potential research areas. We performed a systematic search of the available literature from 1 April 1998 to 31 December 2018 involving newborn screening and diabetes using OVID, MEDLINE, Cochrane and the PROSPERO register, utilizing a modified extrac

SUBMITTER: Estrella JFGL 

PROVIDER: S-EPMC7602529 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature