ConCysFind: a pipeline tool to predict conserved amino acids of protein sequences across the plant kingdom.

ABSTRACT:

Background

Post-translational modifications (PTM) of amino acid (AA) side chains in peptides control protein structure and functionality. PTMs depend on the specific AA characteristics. The reactivity of cysteine thiol-based PTMs are unique among all proteinaceous AA. This pipeline aims to ease the identification of conserved AA of polypeptides or protein families based on the phylogenetic occurrence in the plant kingdom. The tool is customizable to include any species. The degree of AA conservation is taken as indicator for structural and functional significance, especially for PTM-based regulation. Further, this pipeline tool gives insight into the evolution of these potentially regulatory important peptides.

Results

The web-based or stand-alone pipeline tool Conserved Cys

SUBMITTER: Moore M 

PROVIDER: S-EPMC7603750 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature