Risk factors associated with renal crescentic formation in pediatric Henoch-Schonlein purpura nephritis: a retrospective cohort study.

ABSTRACT:

Background

The long-term prognosis of Henoch-Schönlein purpura (HSP) depends on the severity of renal involvement, and crescent formation is considered an important risk factor for poor prognosis of Henoch-Schönlein purpura nephritis (HSPN). The objective of this study was to evaluate factors affecting crescent formation in children with HSPN.

Methods

Demographic factors, clinical characteristics, and laboratory data of children with HSPN with or without crescents were retrospectively analyzed. Univariate and multivariate logistic regression analyses were used to determine the risk factors of crescent formation in HSPN.

Results

A total of 191 children with HSPN were enrolled in the study. There were 107 (56%) males and 84 (44%) females, with a median age of 7 years (r

SUBMITTER: Song YR 

PROVIDER: S-EPMC7604931 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature