Heterogeneity of Balo's concentric sclerosis: a study of eight cases with different therapeutic concepts.

ABSTRACT:

Background

Baló's Concentric Sclerosis (BCS) is a rare heterogeneous demyelinating disease with a variety of phenotypes on Magnetic Resonance Imaging (MRI). Existing literature lacks data especially on the therapeutic approach of the disease which we intended to elucidate by means of suggesting a new possible BCS classification and introducing different therapeutic concepts based on each BCS-subgroup characteristics.

Methods

We present a retrospective study of eight treated patients with BCS-type lesions, emphasizing on MRI characteristics and differences on therapeutic maneuvers.

Results

Data analysis showed: at disease onset the BCS-type lesion was tumefactive (size ≥2 cm) in 6 patients, with a mean size of 2.7 cm (± 0.80 SD); a coexistence of MS-like plaques on bra

SUBMITTER: Tzanetakos D 

PROVIDER: S-EPMC7604966 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature