Genome variation and population structure among 1142 mosquitoes of the African malaria vector species <i>Anopheles gambiae</i> and <i>Anopheles coluzzii</i>.

ABSTRACT: Mosquito control remains a central pillar of efforts to reduce malaria burden in sub-Saharan Africa. However, insecticide resistance is entrenched in malaria vector populations, and countries with a high malaria burden face a daunting challenge to sustain malaria control with a limited set of surveillance and intervention tools. Here we report on the second phase of a project to build an open resource of high-quality data on genome variation among natural populations of the major African malaria vector species Anopheles gambiae and Anopheles coluzzii We analyzed whole genomes of 1142 individual mosquitoes sampled from the wild in 13 African countries, as well as a further 234 individuals comprising parents and progeny of 11 laboratory crosses. The data resource includes high-

SUBMITTER: Anopheles gambiae 1000 Genomes Consortium 

PROVIDER: S-EPMC7605271 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature