Lack of association of antihypertensive drugs with the risk and severity of COVID-19: A meta-analysis.

ABSTRACT:

Background

The association of antihypertensive drugs with the risk and severity of COVID-19 remains unknown.

Methods and results

We systematically searched PubMed, MEDLINE, The Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov, and medRxiv for publications before July 13, 2020. Cohort studies and case-control studies that contain information on the association of antihypertensive agents including angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), calcium-channel blockers (CCBs), β-blockers, and diuretics with the risk and severity of COVID-19 were selected. The random or fixed-effects models were used to pool the odds ratio (OR) with 95% confidence interval (CI) for the outcomes. The literat

SUBMITTER: Ren L 

PROVIDER: S-EPMC7605745 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature