A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.

ABSTRACT: A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback mechanism to suppress inflammation. However, several lines of clinical evidence suggest that dramatic early proinflammatory IL-10 elevation may play a pathological role in COVID-19 severity.

SUBMITTER: Lu L 

PROVIDER: S-EPMC7605819 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature