The effect of massive transfusion protocol implementation on the survival of trauma patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Massive transfusion protocol (MTP) has been widely adopted for the care of bleeding trauma patients but its actual effectiveness is unclear. An earlier meta-analysis on the implementation of MTP for injured patients from 1990 to 2013 reported that only 2 out of 8 studies showed statistical improvement in survival. This study aimed to conduct an updated systematic review and meta-analysis to evaluate the effect of implementing an MTP on the mortality of trauma patients.

Materials and methods

MEDLINE, PubMed, Cochrane Library and Google scholar databases were systematically searched for relevant studies published from 1^st January 2008 to 30^th September 2019 using a combination of keywords and additional manual searching of reference lists. Incl

SUBMITTER: Consunji R 

PROVIDER: S-EPMC7605882 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature