Anticoagulation in Italian patients with venous thromboembolism and thrombophilic alterations: findings from START2 register study.

ABSTRACT:

Background

Randomised control trials have assessed the efficacy and safety of direct oral anticoagulants in the prophylaxis and treatment of venous thromboembolism (VTE). Positive but limited results have been reported in patients with inherited thrombophilia. Using an Italian, multicentre, prospective registry of consecutive patients presenting with symptomatic, acute VTE, we aimed to assess which factors are involved in making the choice of the drug that best fits the patient's risk profile in a large real-world setting of VTE patients.

Materials and methods

We investigated 4,866 VTE patients who took oral anticoagulants in the period between 2012 and April 2018 to prevent a new thromboembolic episode.

Results

The large majority of patients who underwent thrombophil

SUBMITTER: Margaglione M 

PROVIDER: S-EPMC7605886 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature