Longitudinal analysis of complete blood count parameters in advanced-stage lung cancer patients.

ABSTRACT:

Background

Metastatic lung cancer is a debilitating disease, but with the advances in immunotherapy, therapeutic options have vastly increased. Numerous complete blood count parameters (CBC) have been described as easily accessible biomarkers that might predict response to immunotherapy. However, to date, no comprehensive study has been performed on the longitudinal changes of these parameters during cancer progression.

Methods

The clinicopathological variables and CBC parameters of 986 advanced stage lung cancer patients were retrospectively analyzed. Blood tests were performed as part of the routine checkup and the results were recorded at the time of the diagnosis of the primary tumor, the diagnosis of brain or bone metastases, and also during the last available follow-up

SUBMITTER: Rojko L 

PROVIDER: S-EPMC7605999 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature