Recommendations for Long-Term Follow-up of Adults with Heritable Retinoblastoma.

ABSTRACT:

Purpose

To generate recommendations for long-term follow-up of adult survivors of heritable retinoblastoma.

Design

We convened a meeting of providers from retinoblastoma centers around the world to review the state of the science and to evaluate the published evidence.

Participants

Retinoblastoma is a rare childhood cancer of the retina. Approximately 40% of retinoblastoma cases are heritable, resulting from a germline mutation in RB1. Dramatic improvements in treatment and supportive care have resulted in a growing adult survivor population. However, survivors of heritable retinoblastoma have a significantly increased risk of subsequent malignant neoplasms, particularly bone and soft tissue sarcomas, uterine leiomyosarcoma, melanomas, and radiotherapy-related central

SUBMITTER: Tonorezos ES 

PROVIDER: S-EPMC7606265 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature