Cognitive complaints by hematopoietic cell transplantation recipients and change in neuropsychological performance over time.

ABSTRACT:

Purpose

Hematopoietic stem cell transplant (HSCT) recipients are at risk for cognitive decline. Cross-sectional studies show patients' complaints of cognitive decline do not correlate well with concurrently measured objective neuropsychological performance, but rather with emotional variables and health-related quality of life. This longitudinal study investigated whether patient self-report of cognitive status would be concordant with objectively measured neuropsychological performance after accounting for change from their own pre-transplant objective baseline.

Methods

Pre-HSCT and at 30 and 100 days post-HSCT, 46 patients underwent computerized neuropsychological testing (CogState) and completed surveys assessing patient-reported cognitive complaints, emotional symptoms (

SUBMITTER: LaLonde L 

PROVIDER: S-EPMC7606345 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature