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An Evidence-Based Review of Galcanezumab for the Treatment of Migraine.


ABSTRACT:

Purpose of review

This is a comprehensive review of the current literature on the usage of galcanezumab for migraine treatment. It reviews the biology, pathophysiology, epidemiology, diagnosis, and conventional treatment of migraines, then compares the literature available for galcanezumab with historical treatment options.

Recent findings

Migraine is a common headache disorder and constitutes a significant source of distress from both a personal and societal perspective. Conventional treatment includes abortive and preventive treatment. Treatment options are limited and may be only partially or minimally effective in some of the population. Recent evidence points to metabolic changes in the brain as possible causes of migraine, via reduced available energy or a spiking need

SUBMITTER: Urits I 

PROVIDER: S-EPMC7606392 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature