Impact of Formulary Restrictions on Antiepileptic Drug Dispensation Outcomes.

ABSTRACT:

Introduction

The aim of this analysis was to assess the relationship between formulary restrictions and antiepileptic drug (AED) dispensation in patients with focal seizure (FS).

Study design

A retrospective cohort analysis was conducted using data from Symphony Health's Integrated Dataverse® (1 April 2015-30 June 2018).

Methods

This study included two patient populations: the overall patient population (N = 54,097) and a pediatric population (< 18 years) (N = 12,610). Cohorts were defined based on approval or rejection of the index AED claim. Study outcomes were prescription life cycle analysis, proportion of patients with dispensation, time to dispensation, and likelihood of successful dispensation. A multivariable Cox proportional hazards model was estimated to stu

SUBMITTER: Mehta D 

PROVIDER: S-EPMC7606428 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature