A comparison of the Avisoft (v.5.2) and MATLAB Mouse Song Analyzer (v.1.3) vocalization analysis systems in C57BL/6, Fmr1-FVB.129, NS-Pten-FVB, and 129 mice.

ABSTRACT:

Background

Communicative behaviors play a vital role in mammals and are highly relevant to human neurodevelopmental conditions. Mice produce communicative vocalizations that occur in the ultrasonic range, which are commonly analyzed within the Avisoft recording system. Fully automated programs such as the Mouse Song Analyzer in MATLAB, have been developed to analyze USVs in a shorter time period, however, no study has compared the accuracy of MATLAB to Avisoft.

New method

In order to determine MATLAB's accuracy, we used data from four different mouse strains and assessed whether the total number of USVs detected was similar between systems.

Results

We found that there was a high correlation between systems for the number of USVs emitted from C57BL/6 and NS-Pten mice h

SUBMITTER: Binder M 

PROVIDER: S-EPMC7606442 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature