Associations of Reading Efficiency with White Matter Properties of the Cerebellar Peduncles in Children.

ABSTRACT: Reading in children has been associated with microstructural properties of the cerebellar peduncles, the white matter pathways connecting the cerebellum to the cerebrum. In this study, we used two independent neuroimaging modalities to assess which features of the cerebellar peduncles would be associated with reading. Twenty-three 8-year-old children were evaluated on word reading efficiency and imaged using diffusion MRI (dMRI) and quantitative T1 relaxometry (qT1). We segmented the superior (SCP), middle, and inferior cerebellar peduncles and extracted two metrics: fractional anisotropy (FA) from dMRI and R1 from qT1. Tract-FA was significantly correlated with tract-R1 in left and right SCPs (left: r_P(21) = .63, right: r_P(21) = .76, p ≤ .001) suggesting that FA of t

SUBMITTER: Bruckert L 

PROVIDER: S-EPMC7606658 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature