Effects of Induced Astigmatism on Spectral Domain-OCT Angiography Quantitative Metrics.

ABSTRACT:

Purpose

To analyze the effect of induced astigmatism on en-face spectral-domain optical coherence tomography angiography quantitative metrics.

Design

Prospective crossover study.

Methods

Normal eyes without astigmatism and with 0.75, 1.75, and 2.75 diopters (D) of with-the-rule (WTR) astigmatism were imaged using a 3 × 3-mm scan pattern SD-OCTA CIRRUS 5000 HD-OCT with AngioPlex (Carl Zeiss Meditec, Dublin, CA, USA). Quantitative parameters, including foveal avascular zone metrics, parafoveal vessel length density (VD), and perfusion density (PD) were corrected for magnification secondary to axial length and analyzed. Univariate linear regressions were performed within each eye to correlate quantitative metrics to the level of an induced astigmatic cylinder.

Results

SUBMITTER: Jung JJ 

PROVIDER: S-EPMC7606665 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature