Neurobehavioral outcomes in young adults with perinatally acquired HIV.

ABSTRACT:

Background

With combination antiretroviral therapy (cART), infants with perinatally acquired HIV (pHIV) are living into adolescence and adulthood. Worldwide, many have not received cART in the first years of life, and challenges of adolescence complicate transition to adulthood. Neurobehavioral outcomes in pHIV young adults (pHIVAd) are infrequently reported.

Objectives

To examine neurobehavioral characteristics of pHIVAd ages 21-30 years, and to compare them with age-matched young adults infected in the second or third decade of life (HIVagematch), and older adults with similar duration HIV disease (HIVOA).

Methods

A comprehensive neuropsychological test battery and questionnaires to determine cognitive function and mood, and reviews of neuromedical and behavioral re

SUBMITTER: Coutifaris P 

PROVIDER: S-EPMC7606727 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature