Enantioselective S-H Insertion Reactions of α-Carbonyl Sulfoxonium Ylides.

ABSTRACT: The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee) and yields (up to 97 %) are achieved for 31 examples in S-H insertion reactions of aryl thiols and α-carbonyl sulfoxonium ylides.

SUBMITTER: Momo PB 

PROVIDER: S-EPMC7606806 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature