A self-reported Frailty Index predicts long-term mortality in hospitalized patients with cirrhosis.

ABSTRACT:

Background

Frailty is a syndrome that diminishes the potential for functional recovery in liver cirrhosis (LC). However, its utility is limited due to sole reliance on physical performance, especially in hospitalized patients. We investigate the predictive value of a modified self-reported Frailty Index in cirrhotics, and identify which health deficits play more important roles.

Methods

Consecutive LC patients were assessed by our frailty scale. Outcomes of interest were mortality for 90-day, 1-year and 2-year. Independent predictors were identified by multivariate Cox regression. Receiver operating characteristic curve (ROC) was performed to evaluate discriminative ability. We used a combination of stepwise selection, best subset selection, and Akaike information criteria (

SUBMITTER: Deng Y 

PROVIDER: S-EPMC7607105 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature