Partial proteomic analysis of brown widow spider (Latrodectus geometricus) venom to determine the biological activities.

ABSTRACT: Spiders use their venom for defence and to capture prey. These venoms contain a cocktail of biologically active compounds that display several different biological activities, such as large molecules and small molecules including peptides, proteins/enzymes, and other components. Thus, venom constituents have attracted the attention of biochemists and pharmacologists over the years. The brown widow spider (Latrodectus geometricus) is a venomous spider found worldwide, including in Thailand. This spider causes human injuries, and the venom has many potential applications. In this study, we investigated the complexity and pharmacology of brown widow spider venom. Spider crude venom was investigated using partial proteome techniques and enzymatic activity, toxicity, and antibacterial ac

SUBMITTER: Khamtorn P 

PROVIDER: S-EPMC7607507 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature